Watch Dr Bakris and Dr Kramer discuss how you can manage your patients like Kathy with KERENDIA.
UACR, or urinary albumin-to-creatinine ratio, measures kidney damage and is used (along with eGFR) to diagnose CKD and assess risk of CV mortality in patients with CKD. KDIGO recommends that a patient’s CKD be staged based on eGFR, urinary albumin, and cause.1,2
The 2022 ADA Guidelines recommend assessing both UACR and eGFR at least annually in all patients with T2D, regardless of treatment regimen. Patients with T2D and albuminuria (UACR) ≥300 mg/g and/or eGFR 30 to 60 mL/min/1.73 m2 should be monitored at least twice per year. Additionally, for patients with CKD who have urinary albumin >300 mg/g, the ADA recommends a reduction of ≥30% in mg/g urinary albumin to slow CKD progression.3
References: 1. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. Kidney Intl Suppl. 2013;3(1):1-150. 2. Campion CG, et al. Can J Kidney Health Dis. 2017;4. doi:10.1177/2054358117705371. 3. American Diabetes Association Professional Practice Committee. Chronic kidney disease and risk management: standards of medical care in diabetes—2022. Diabetes Care. 2022;45(suppl 1):S175-S184. doi:10.2337/dc22-S011.
Adult patients with CKD associated with T2D may be appropriate for KERENDIA. The FIDELIO-DKD trial studied patients with CKD associated with T2D, defined as either having a UACR of 30 to 300 mg/g, eGFR 25 to 60 mL/min/1.73 m2 and diabetic retinopathy, or as having a UACR of ≥300 mg/g and an eGFR of 25 to 75 mL/min/1.73 m2.1 For more information, visit The KERENDIA patient section of the website.
Reference: 1. KERENDIA (finerenone) [prescribing information]. Whippany, NJ: Bayer HealthCare Pharmaceuticals, Inc.; July 2021.
Access Services by Bayer is working with CoverMyMeds® to provide the support your patients count on with the enhanced services you can trust from CoverMyMeds®. We provide visibility into the entire patient journey and reduce time to therapy through enhanced services within your workflow including appeals support. Go to CoverMyMeds.com to help your patients start KERENDIA today.
If you do not use CoverMyMeds®, Bayer provides sample Letters of Medical Necessity and Medical Exception here.
Offices may also refer to the KERENDIA Prior Authorization and Medical Exceptions Guide for helpful tips when submitting these authorization requests.
The price that each patient pays for KERENDIA depends on what type of prescription drug plan they have and which pharmacy they go to. We are committed to helping your patients start KERENDIA by supporting their insurance and affordability challenges. Patients who need help paying for their KERENDIA prescription should call 1-888-KERENDIA (537-3634) or visit www.KERENDIA.com to learn more about the affordability solutions offered by Bayer.
ADA=American Diabetes Association; CKD=chronic kidney disease; CV=cardiovascular; eGFR=estimated glomerular filtration rate; KDIGO=Kidney Disease: Improving Global Outcomes; T2D=type 2 diabetes; UACR=urine albumin-to-creatinine ratio.
KERENDIA is indicated to reduce the
risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D)
Measure serum potassium periodically during treatment with KERENDIA and adjust dose accordingly. More frequent monitoring may be necessary for patients at risk for hyperkalemia, including those on concomitant medications that impair potassium excretion or increase serum potassium
Please read the Prescribing Information for KERENDIA.